Promethazine HCl Oral Remedy needs to be utilised with warning in sufferers with bone-marrow depression. Leukopenia and agranulocytosis have already been noted, normally when Promethazine (Promethazine HCl) has been Utilized in association with other acknowledged marrow-poisonous agents.

The most common side effects are drowsiness, adjustments in blood pressure, skin reactions, blood mobile alterations and breathing issues. Improved excitability or irregular actions may well occur following a person dose of promethazine. If they do, speak to your doctor about utilizing An additional medicine.

Respiration challenges (respiratory depression)that can lead to Dying and opioid withdrawal can occur if You begin having or stop using other medicines whilst taking Promethazine Hydrochloride and Codeine Phosphate Oral Solution, including:

Pregnancy Exams: Diagnostic pregnancy exams based upon immunological reactions amongst HCG and anti-HCG could result in Untrue-detrimental or Untrue-optimistic interpretations.

e., numerous copies of the gene for cytochrome P450 isoenzyme 2D6 or higher morphine concentrations). Young children with snooze apnea may be particularly delicate to the respiratory depressant consequences of codeine.

There isn't any common agreement about specific pharmacological cure regimens for uncomplicated NMS.

For nausea and vomiting in young children, the usual dose is 0.five mg for each pound of physique body weight, as well as dose really should be adjusted to the age and excess weight with the client and also the severity in the affliction currently being addressed.

As a consequence of inconsistencies involving the drug labels on DailyMed and also the tablet photos provided by RxImage, we no more Exhibit the RxImage pill photographs associated with drug labels.

Warning ought to be exercised when administering Promethazine HCl Oral Resolution to pediatric patients two decades of age and more mature as a result of opportunity for lethal respiratory melancholy. Respiratory despair and apnea, from time to time linked to Loss of life, are strongly linked to Promethazine solutions and they are in a roundabout way related to individualized weight-based dosing, which might if not permit Protected administration.

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As a result of inconsistencies among the drug labels on DailyMed as well as the pill visuals provided by RxImage, we no longer Display screen the RxImage tablet pictures related to drug labels.

Hemodialysis just isn't routinely used to enhance the elimination of codeine or promethazine from the body.

The phosphate salt of codeine happens as white, needle-shaped crystals read more or white crystalline powder. Codeine phosphate is freely soluble in water and slightly soluble in alcohol.

Promethazine is very well absorbed from the gastrointestinal tract. Clinical outcomes are obvious within just 20 minutes right after oral administration and generally previous 4 to six several hours, although they may persist assuming that twelve hrs.